IT1182723B - Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio - Google Patents

Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio

Info

Publication number
IT1182723B
IT1182723B IT47844/85A IT4784485A IT1182723B IT 1182723 B IT1182723 B IT 1182723B IT 47844/85 A IT47844/85 A IT 47844/85A IT 4784485 A IT4784485 A IT 4784485A IT 1182723 B IT1182723 B IT 1182723B
Authority
IT
Italy
Prior art keywords
disregrates
tablet
storage
active substance
pharmaceutical active
Prior art date
Application number
IT47844/85A
Other languages
English (en)
Italian (it)
Other versions
IT8547844A0 (it
IT8547844A1 (it
Inventor
Dr Helmut Kopf
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IT8547844A0 publication Critical patent/IT8547844A0/it
Publication of IT8547844A1 publication Critical patent/IT8547844A1/it
Application granted granted Critical
Publication of IT1182723B publication Critical patent/IT1182723B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT47844/85A 1984-03-23 1985-03-21 Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio IT1182723B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1465/84A CH658188A5 (de) 1984-03-23 1984-03-23 Lagerstabile schnellzerfallende pharmazeutische presslinge.

Publications (3)

Publication Number Publication Date
IT8547844A0 IT8547844A0 (it) 1985-03-21
IT8547844A1 IT8547844A1 (it) 1986-09-21
IT1182723B true IT1182723B (it) 1987-10-05

Family

ID=4211107

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47844/85A IT1182723B (it) 1984-03-23 1985-03-21 Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio

Country Status (26)

Country Link
US (1) US4666703A (en])
JP (1) JPS60209518A (en])
AT (1) AT394310B (en])
AU (1) AU579355B2 (en])
BE (1) BE901994A (en])
CA (1) CA1239348A (en])
CH (1) CH658188A5 (en])
DE (1) DE3510129A1 (en])
DK (1) DK162375C (en])
ES (1) ES8702786A1 (en])
FI (1) FI82187C (en])
FR (1) FR2561524B1 (en])
GB (1) GB2157170B (en])
GR (1) GR850717B (en])
HK (1) HK73090A (en])
IE (1) IE57954B1 (en])
IL (1) IL74666A (en])
IT (1) IT1182723B (en])
LU (1) LU85817A1 (en])
NL (1) NL8500856A (en])
NO (1) NO170125C (en])
NZ (1) NZ211537A (en])
PT (1) PT80147B (en])
SE (1) SE8501370L (en])
SG (1) SG46890G (en])
ZA (1) ZA852160B (en])

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GB8521494D0 (en) * 1985-08-29 1985-10-02 Zyma Sa Controlled release tablet
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US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
DE3776116D1 (de) * 1986-12-30 1992-02-27 American Cyanamid Co Zusammensetzung die ein polycarbophil enthaelt.
GB8707416D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
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US4789547A (en) * 1987-06-17 1988-12-06 Warner-Lambert Company Transdermal matrix system
US4904477A (en) * 1987-07-08 1990-02-27 American Home Products Corporation Spray dried ibuprofen compositions
US4927639A (en) * 1989-02-02 1990-05-22 Warner-Lambert Company Modified release gemfibrozil composition
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5122384A (en) * 1989-05-05 1992-06-16 Kv Pharmaceutical Company Oral once-per-day organic nitrate formulation which does not induce tolerance
DE3937455A1 (de) * 1989-11-10 1991-05-16 Nordmark Arzneimittel Gmbh Antacidatabletten
EP0462066A1 (en) * 1990-06-15 1991-12-18 Warner-Lambert Company Amorphous gemfibrozil
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
BE1004461A5 (fr) * 1991-01-30 1992-11-24 Wellcome Found Comprimes dispersables dans l'eau.
ES2059260B1 (es) * 1992-10-06 1995-04-16 Espanola Prod Quimicos Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua.
DE4317172A1 (de) * 1993-05-22 1995-01-05 Rhone Poulenc Rorer Gmbh Geschmacksneutrale und schnellfreisetzende Buflomedil-Hydrochlorid-Arzneiform und Herstellungsverfahren desselben
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
ES2082723B1 (es) * 1994-07-20 1996-10-01 Lilly Sa Formulacion farmaceutica de fluoxetina en forma dispersable.
US5674529A (en) * 1995-06-06 1997-10-07 Church & Dwight Co., Inc. Alkalinizing potassium salt controlled release preparations
ES2224184T3 (es) * 1995-11-14 2005-03-01 ABBOTT GMBH & CO. KG Preparaciones estabilizadas de hormonas tiroideas y metodos para su fabricacion.
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
ES2188928T3 (es) * 1996-04-26 2003-07-01 Shionogi & Co Pastilla de liberador-rapido s1452.
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
HU221435B (en) * 1998-02-20 2002-10-28 Egyt Gyogyszervegyeszeti Gyar Pellet-based pharmaceutical composition of controlled release with high content of potassium-chloride, and process for it's production
FR2781793B1 (fr) * 1998-08-03 2001-07-20 Prographarm Lab Procede de fabrication de granules de gabapentine enrobes
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6500462B1 (en) * 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
DE60128215T2 (de) 2000-04-20 2008-01-10 Novartis Ag Beschichtungszusammensetzung zur geschmacksmaskierung
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
US6699315B2 (en) 2000-11-28 2004-03-02 Fmc Corporation Edible PGA coating composition
MXPA03007337A (es) * 2001-02-15 2005-03-07 King Pharmaceuticals Inc Composicion farmaceutica y de hormona tiroidea estabilizada y metodo de preparacion de la misma.
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US20030198671A1 (en) * 2001-08-10 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique plasma AUC properties
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US20030199586A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Unique levothyroxine aqueous materials
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US20030190359A1 (en) * 2001-10-29 2003-10-09 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
US6645526B2 (en) * 2001-11-13 2003-11-11 Mylan Pharmaceuticals, Inc. Storage stable thyroxine active drug formulations and methods for their production
US20030099699A1 (en) 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
EP1488811A1 (en) * 2002-03-06 2004-12-22 Kyowa Hakko Kogyo Co., Ltd. Tablets quickly disintegrating in oral cavity
US20040029959A1 (en) * 2002-08-08 2004-02-12 John Devane Isosorbide mononitrate compositions and methods of their use
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
US20100297226A1 (en) * 2006-06-01 2010-11-25 Dexcel Pharma Technologies Ltd. Multiple unit pharmaceutical formulation
MX2009006699A (es) * 2006-12-21 2009-06-30 Mallinckrodt Inc Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos.
WO2008079342A2 (en) * 2006-12-21 2008-07-03 Mallinckrodt Inc. Composition of and method for preparing orally disintegrating tablets
CN101380474B (zh) * 2007-09-06 2012-07-25 北京大学 用于口服制剂的pH敏感性固体药物组合物及制备方法
CA2936748C (en) 2014-10-31 2017-08-08 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

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DE2200778B2 (de) * 1971-01-13 1974-04-18 Sandoz Ag, Basel (Schweiz) Verwendung von hochmolekularem, unlöslichem, quervernetztem Polyvinylpyrrolidon als Sprengmittel in festen Arzneiformen
BE785702A (fr) * 1971-07-14 1972-10-16 Roehm Gmbh Produits de revetement de formes medicamenteuses et leur utilisation
GB1540754A (en) * 1976-03-10 1979-02-14 Wellcome Found Tablet formulation
JPS5535031A (en) * 1978-09-04 1980-03-11 Shin Etsu Chem Co Ltd Enteric coating composition
US4505896A (en) * 1979-04-19 1985-03-19 Elorac, Ltd. Method of treating acne vulgaris and composition
CH642809B (fr) * 1980-11-07 Longines Montres Comp D Montre avec un mecanisme de quantieme perpetuel.
EP0052076B1 (de) * 1980-11-12 1985-05-29 Ciba-Geigy Ag Schnellzerfallende Arzneimittel-Presslinge
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
IT1168014B (it) * 1981-08-05 1987-05-20 Erba Farmitalia Forme farmaceutiche a cessione protratta

Also Published As

Publication number Publication date
HK73090A (en) 1990-09-21
IL74666A (en) 1988-11-30
SE8501370D0 (sv) 1985-03-20
JPS60209518A (ja) 1985-10-22
DK162375B (da) 1991-10-21
NO170125B (no) 1992-06-09
CA1239348A (en) 1988-07-19
DK130685A (da) 1985-09-24
ES541513A0 (es) 1987-01-16
AT394310B (de) 1992-03-10
PT80147B (pt) 1987-10-20
FI851114L (fi) 1985-09-24
GB2157170B (en) 1988-01-20
FI851114A0 (fi) 1985-03-20
IE57954B1 (en) 1993-05-19
IE850744L (en) 1985-09-23
GB2157170A (en) 1985-10-23
GR850717B (en]) 1985-07-19
IT8547844A0 (it) 1985-03-21
ZA852160B (en) 1985-11-27
ATA86885A (de) 1991-09-15
AU579355B2 (en) 1988-11-24
SG46890G (en) 1990-08-17
DK162375C (da) 1992-03-09
ES8702786A1 (es) 1987-01-16
DK130685D0 (da) 1985-03-22
AU4028785A (en) 1985-09-26
CH658188A5 (de) 1986-10-31
DE3510129A1 (de) 1985-10-03
JPH0574568B2 (en]) 1993-10-18
BE901994A (fr) 1985-09-23
IT8547844A1 (it) 1986-09-21
FR2561524A1 (fr) 1985-09-27
NZ211537A (en) 1988-03-30
US4666703A (en) 1987-05-19
FR2561524B1 (fr) 1990-01-12
NO170125C (no) 1992-09-16
FI82187C (fi) 1991-02-11
SE8501370L (sv) 1985-09-24
FI82187B (fi) 1990-10-31
NO851170L (no) 1985-09-24
IL74666A0 (en) 1985-06-30
LU85817A1 (de) 1985-12-12
PT80147A (en) 1985-04-01
NL8500856A (nl) 1985-10-16
GB8506758D0 (en) 1985-04-17

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940322